Abstract

With the worldwide need for uniformity in 3D cell culture methods, the focus is no longer whether physical characterization will factor into a workflow, but how is it possible to precisely assess the homogeneity of the 3D sample populations. The scientific landscape strongly requires researchers to correlate physical parameter with those derived from the commonly used in vitro tests. And most importantly, when it comes to culturing 3D cell models as spheroids or organoids, their biophysics holds a biological relevance, thereby representing a potential source of data variability.

In this webinar, we will showcase the W8 physical cytometer – the only fully automated system for the physical characterization of 3D sphere-like biological samples. The combination of CellDynamics’ groundbreaking microfluidic technology with bright-field image-based analysis simultaneously provides a sample’s mass density, weight and size values in less than 10 minutes. In addition, the W8 is able to  sort a target sub-population using pre-selected ranges for these parameters.