FluidFM® OMNIUM Platform

Description

THE SAME CELL. BEFORE AND AFTER.

From Single-Cell Biology to Same-Cell Biology

Biology has traditionally relied on snapshots, measuring different cells at different moments and inferring causation from correlation. FluidFM® technology preserves cell viability during measurement, perturbation, or precise gene editing, revealing true cause and effect within the same cell.

This is Same-Cell Biology, a new approach to understanding how living cells behave, respond, and change.

FluidFM® Technology

FluidFM® technology combines a hollow AFM cantilever, a microfluidic channel, and force feedback into a probe for gentle manipulation of a single living cell without damaging it, with the precision to extract material or inject payloads, while the cell keeps living, dividing, and responding.

Specification

omplete OMNIUM full system specifications.

Metric	Spec	Why it matters
Microscopy	Objectives	10x, 20x, 40x long-distance
	Imaging	Brightfield
	Configuration	Customizable
	Focus stroke / increment	10.5 mm stroke, 0.01 µm increment
Fluorescence	Light source	White LED, 360–770 nm, 25,000 h lifetime
	Filter sets	3 standard, Red, Green, Blue, expandable to 8
	Filter switch	300 ms, motorized turret
Camera	Sensor	CMOS Color, 2.35 MP, 12-bit, 2nd camera option available
Incubation	Temperature	37°C ± 0.1°C
	CO₂	1–15%, ± 0.1% accuracy
	Sterility	HEPA filter + UV sterilization
	Casing	Polycarbonate, optimized for fluorescence imaging
FluidFM	Pressure	−800 to +1,000 mbar, 0.5 mbar resolution
	Stage	Nanometer-precise XY + Z, < 500 nm / < 5 nm repeatability
	Probe exchange	Motorized, automated
Sample handling	Containers	Multi-well plates, up to 2x standard, dishes, glass-bottom dishes

Sample Compatibility: Your standard cell culture ware fits the system. No special consumables needed.

Expand Your System: Modular expansion with application-specific probes, consumables, and software.

Applications

MULTIPLE SAME-CELL WORKFLOWS

One instrument for live-cell manipulation, measurement, and analysis

Use FluidFM OMNIUM across live-cell transcriptomics, vector-free delivery, cell isolation, force spectroscopy, and bioprinting workflows.

Live-seq

Repeated live-cell transcriptomics from the same living cell across time. Sample, perturb, and re-sample while preserving cell viability.

Learn more about Live-seq →

Vector-free cargo delivery

Deliver mRNA, proteins, CRISPR reagents, or nanomaterials directly into living cells without viral vectors or electroporation.

Learn more about CellEDIT →

Single-cell pick & place

Select, relocate, and organize individual living cells with image-verified precision for array generation, co-culture design, and population sorting.

Single-cell isolation

Isolate individual living cells for downstream analysis, monoclonal expansion, and image-verified single-cell workflows.

Automated force spectroscopy

Quantify cell adhesion, stiffness, and mechanical response at single-cell resolution with automated force measurements across large experimental datasets.

Bioprinting

Pattern biomolecules and living cells in defined spatial arrangements from sub-micron features to centimetre-scale constructs.

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