Physical Cytometer: spheroids & organoids

Physical Cytometer: spheroids & organoids

The W8 (pronounced ‘weight’) from Cell Dynamics is a physical cytomter for the quantitative measurement of size, weight and mass density for spherical biological samples. It can be used for single cell suspensions to 3D spheroids and organoids  ranging from 20 microns to 500 microns.

Accurate and precise knowledge of mass density, shape, size and weight of spheroid like cells or cell aggregates provides valuable insights into understanding processes into outcomes for assays. Our early applications include cancer research, tissue engineering and regenerative medicine. The W8 physical cytometry system offers a paradigm shift by enabling standardisation of 3D heterogeneous models.

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Description

The W8 is a physical cytomter for the quantitative measurement of size, weight, and mass density of spherical biological material such as spheroids and organoids.

Gathering precise information on mass density, shape, size and weight of cells or cell aggregates, is crucial for several applications as for cancer research, tissue engineering and regenerative medicine. Although few technical solutions have been presented for single cell analysis, scientists still lack methods for physical cytometry and standardization of 3D Biology heterogenous models.

With an intuitive user Interface and automated data analysis in spreadsheet files, the W8 technology offers a groundbreaking weighing method to perform quality control of 3D cell culture and quantitatively evaluate in vitro assays from the physical point of view.

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